Ever since his wife suffered burns all over her body as a result of a car accident, the plastic surgeon Robert Ledgard has been interested in creating a new kind of skin that could have saved her. Marilia, the woman who has looked after him since the day he was born, is his accomplice. But he also needs a human guinea pig. Every year that passes dozens of young people of both sexes have disappeared from their homes, many of them by choice. One of these young people ends up sharing the magnificent mansion of El Cigarral with Robert and Marilia, but it's not by choice.